In the East African botanical plate, various ethnic groups cherish their traditions and embrace distinguished use of medicinal plants in the management of ailments. Research shows 145 plant species from 125 genera spread across 55 families were found to have been reported for cancer treatment in Kenya. The malignancies treated using the herbal remedies include squamous cell carcinoma of the gum, prostate, blood, bone, breast, colorectal, colon, oesophageal, lung, liver, skin, stomach, throat and uterine cancers. Most of the identified species have reported anticancer activities. Are they reliable ?